- CalciumCalcium: According to a clinical trial, safflower oil may significantly decrease leukocyte-ionized calcium (55). These results are supported by a similar, earlier clinical trial by the same author (56).
- LipidsLipids: According to clinical trials and laboratory study, ingestion of safflower oil may decrease serum total cholesterol, HDL, LDL, apolipoprotein B, and malondialdehyde-LDL (30; 87; 88; 89; 90; 91; 92). However, some clinical trials found that safflower may increase some serum lipids, including cell cholesterol in the plasma, and increase triglyceride-rich lipoproteins (93; 94; 57; 95); several other clinical trials found that safflower oil did not significantly change any of the lipid/lipoprotein values (96; 97; 98; 99; 100; 101; 78; 102; 92).
- TocopherolTocopherol: According to a clinical trial, tocopherol-stripped safflower oil may decrease plasma tocopherol levels (117).
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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.